1. Click on elements to increase the amount being used. (Once the amount exceeds 4, it resets to zero) 2. Once you believe to have found a correct combination, click the flask. 3. A new element will either be added to the 'Discovered' list, or your mix will be rejected as it either does not create anything or is not yet in the database 4. There are 20+ total things to create, (ex, H2O, CO2)