Green flag I have a theory that Main Toons turn Twisted when they are overcome by emotions, not Ichor. Gourdy misses his parents. He can’t remember them, and crosses out his drawings of them for “not looking right”. His grief led to him turning Twisted. Bassie is terrified of being replaced, specifically by Cocoa. Delilah wanted Cocoa to be the Easter Main, but Bassie was chosen instead. Her fear and sense of inferiority led to her turning Twisted. Bobette was overworked in the Christmas season, making toys for everyone. She couldn’t keep working, but no one cared. She turned Twisted out of shame. Vee was furious after Scraps won all of her game show prizes. She went bitter and secluded herself, eventually turning Twisted out of anger. Astro knows about Twisted Dandy. His sadness over what his friend had become led to him turning Twisted. Pebble does not know about Twisted Dandy. All he knows is that his master vanished. Believing he had failed to protect Dandy, he turned Twisted out of shame. Sprout lost Cosmo to the Ichor corruption. Feeling lost and isolated without his best friend, he turned Twisted out of loneliness. Shelly fears being forgotten. Other Toons seem to show no interest in her. She felt invisible, and turned Twisted out of a sense of not being wanted.
Thanks to CG5 for song and image