Mutation: Aneuploidy in Breast Cancer The presence of an abnormal number of chromosomes in a cell. A human cell usually has 46 chromosomes, but aneuploidy means they have 45 or 47 instead. This happens because chromosomes can fail to attach to the string-like spindles to move to the center of the cell. Aneuploidy is consistently present in virtually all cancers, specifically in the development and progression of most breast cancers. When the processes regulating mitosis are ignored or overridden by a cancer cell, this results in uncontrolled cell division.
Made by Phoebe and Ximena Research & Creative consultation: Phoebe Coding and creative consultation: Ximena Instructions: Click on each cell to see how it goes through mitosis (The numbers are the number of chromosomes in the cell)