Click on the "START" button. Simon will flash three of the colored buttons (and play three tones). You now have a few seconds to click on the colored buttons in the same order that Simon flashed them. If you succeed, Simon will replay the sequence but add another color/tone. The cycle continues until you fail.
An implementation of the memory game "Simon". From Wikipedia: "Simon's tones, on the other hand, were designed to always be harmonic,[2] no matter what order they were played in, and consisted of an A major triad in second inversion: E-note (blue, lower right); C#-note (yellow, lower left); A-note (red, upper right). E-note (green, upper left, an octave lower than blue);"