Use the WASD keys to move and start, use the mouse to aim and shoot, use Q to pick up items (and to swap abilities if random abilities is disabled) and E to use items, use 1,2,3,4 to swap between weapon slots. Different weapons will deal different amounts of damage to enemies. Some weapons are semi-automatic and need to be activated multiple times to shoot continuously, others need to be charged up to fire.
Single Player, Rougelike, Shooter, As of now there are 55 unique weapons in the game. There is a system implemented so that you don't get the same weapons twice (The erase weapons history button will reset this) Enemy sprites break past level 8, whoopsie